![Activation Activation](/uploads/1/2/5/5/125561952/108873964.jpg)
Mast cell activation syndrome (MCAS), is an in which mast cells mistakenly release too many chemical mediators, resulting in several chronic symptoms involving the skin, gastrointestinal tract, heart, respiratory, and neurologic systems. Mast cells are present throughout most of our bodies and secrete different chemicals during allergic reactions. Symptoms include episodes of abdominal pain, cramping, diarrhea, flushing, itching, wheezing, coughing, lightheadedness and potential problems with 'brain fog' or other difficulties with memory.
The cause of MCAS is unknown. Treatment includes several combinations of medications like anti-histamines. Support and advocacy groups can help you connect with other patients and families, and they can provide valuable services.
If you are a physician or mast cell disorder practitioner please submit your information here. Please note that patients are not allowed to submit data on behalf of. Another mother recognized the symptoms I was describing as mast cell activation syndrome (MCAS) and connected me with Dr. Lawrence Afrin at University of Minnesota. Afrin consulted on my daughter’s case, then referred us to Dr. Mark Renneker, a mast cell specialist at the University of California, San Francisco.
Many develop patient-centered information and are the driving force behind research for better treatments and possible cures. They can direct you to research, resources, and services. Many organizations also have experts who serve as medical advisors or provide lists of doctors/clinics. Visit the group’s website or contact them to learn about the services they offer. Inclusion on this list is not an endorsement by GARD.